Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767098 | 1.00 | TRIM24 (0.44) | TRIM24TRIM33ERN1MAPTCYP3A4 | |
| SCHEMBL22531704 | 0.83 | CASP6 (0.51) | TRIM24TRIM33ERN1MAPTCYP3A4 | |
| SCHEMBL27566207 | 0.78 | MAPT (0.34) | ERN1MAPTCYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL27174893 | 0.78 | HSD17B10 (0.39) | MAPTCYP3A4HSD17B10ALDH1A1KDM4E | |
| SCHEMBL6537443 | 0.78 | CASP6 (0.44) | MAPTCYP3A4HSD17B10ALDH1A1KDM4E | |
| SCHEMBL7661967 | 0.77 | TRIM24 (0.50) | TRIM24TRIM33ERN1MAPTALDH1A1 | |
| SCHEMBL6362825 | 0.77 | CASP6 (0.44) | TRIM24TRIM33ERN1MAPTCYP3A4 | |
| SCHEMBL21218382 | 0.76 | TRIM24 (0.47) | TRIM24TRIM33MAPTHSD17B10ALDH1A1 | |
| SCHEMBL29955708 | 0.76 | CYP2A6 (0.47) | TRIM24TRIM33MAPTALDH1A1KDM4E | |
| SCHEMBL671969 | 0.76 | TRIM24 (0.47) | TRIM24TRIM33MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |