Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891555 | 0.78 | ALDH1A1 (0.54) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL2015910 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL28002083 | 0.78 | PDGFRB (0.54) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL14911960 | 0.77 | TDP1 (0.53) | ALDH1A1GAAKDM4ERAB9AGLA | |
| SCHEMBL28289877 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL28184293 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL3661878 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL29956188 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL6965074 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2AKDM4ENPC1 | |
| SCHEMBL28678460 | 0.74 | ALDH1A1 (0.47) | ALDH1A1GAAKMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |