Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028344 | 1.00 | KCNJ1 (0.49) | KCNJ1JAK3KDM4EMEN1ALDH1A1 | |
| SCHEMBL21880021 | 0.82 | KCNJ1 (0.38) | KCNJ1JAK3KDM4EMEN1ALDH1A1 | |
| SCHEMBL22090180 | 0.78 | KCNJ1 (0.46) | KCNJ1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL22789632 | 0.78 | KCNJ1 (0.39) | KCNJ1JAK3KDM4EMEN1ALDH1A1 | |
| SCHEMBL22678487 | 0.78 | KCNJ1 (0.46) | KCNJ1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL27312530 | 0.78 | KCNJ1 (0.36) | KCNJ1 | |
| SCHEMBL13896546 | 0.78 | KCNJ1 (0.46) | KCNJ1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL1474575 | 0.77 | KCNJ1 (0.38) | KCNJ1ALDH1A1 | |
| SCHEMBL7702100 | 0.76 | NOS2 (0.34) | KCNJ1JAK3 | |
| SCHEMBL17068043 | 0.75 | KCNJ1 (0.44) | KCNJ1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |