SCHEMBL29956471

SCHEMBL29956471

Cc1cc(B(O)O)c(Cl)cn1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
PLAU P00749 1/20 0.32
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25635436 1.00 UHRF1 (0.35) UHRF1CYP1A2CYP2A6PLAUSLC6A2
SCHEMBL29951515 0.80 MEN1 (0.32)
SCHEMBL2714951 0.80 MEN1 (0.32)
SCHEMBL29954823 0.78
SCHEMBL29436155 0.77 UHRF1 (0.43) UHRF1CYP1A2CYP2A6
SCHEMBL1932283 0.77 UHRF1 (0.43) UHRF1CYP1A2CYP2A6
SCHEMBL29956857 0.77 NOS3 (0.40) PLAU
SCHEMBL1461927 0.77 NOS3 (0.40) PLAU
SCHEMBL391733 0.77 GPBAR1 (0.32)
SCHEMBL19457709 0.77 PLAU (0.31) PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed