Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560939 | 0.91 | KMT2A (0.38) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL2558609 | 0.89 | CHRM5 (0.49) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL2558448 | 0.88 | KMT2A (0.38) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL2558762 | 0.88 | SIGMAR1 (0.53) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL2557649 | 0.88 | BCHE (0.38) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL15332839 | 0.86 | HTT (0.37) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL2559621 | 0.85 | HTT (0.39) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL29953408 | 0.83 | CHRM5 (0.42) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL2559180 | 0.83 | HTT (0.38) | SIGMAR1GAACYP2C19HTTCHRM5 | |
| SCHEMBL20578751 | 0.82 | SIGMAR1 (0.34) | SIGMAR1GAACYP2C19HTTCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |