Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953254 | 0.87 | MAP4K4 (0.33) | MAP4K4PDE4D | |
| SCHEMBL29953031 | 0.83 | KAT2B (0.40) | MAP4K4CYP11B2PDE4D | |
| SCHEMBL29958451 | 0.78 | MAP4K4 (0.32) | MAP4K4 | |
| SCHEMBL29952660 | 0.78 | PARP10 (0.40) | MKNK1MKNK2PARP1PARP10CYP11B1 | |
| SCHEMBL29951686 | 0.77 | MKNK1 (0.44) | MAP4K4MKNK1MKNK2PARP1PARP10 | |
| SCHEMBL29953869 | 0.77 | MAP4K4 (0.40) | MAP4K4MKNK1MKNK2PARP10PDE4D | |
| SCHEMBL29951309 | 0.75 | POLB (0.32) | MAP4K4 | |
| SCHEMBL29952522 | 0.75 | POLB (0.32) | — | |
| SCHEMBL29955125 | 0.70 | PARP10 (0.41) | MAP4K4MKNK1MKNK2PARP10MAPK8 | |
| SCHEMBL29955580 | 0.69 | POLB (0.37) | MAP4K4MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |