Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955689 | 0.87 | POLB (0.35) | MAP4K4MKNK1MKNK2POLBSCD | |
| SCHEMBL29956377 | 0.82 | KAT2B (0.39) | MAP4K4POLBPDE4APDE4BPDE4C | |
| SCHEMBL29955580 | 0.78 | POLB (0.37) | MAP4K4MKNK1MKNK2POLB | |
| SCHEMBL29951166 | 0.78 | ERN1 (0.41) | MKNK1MKNK2PARP10POLBPDE4A | |
| SCHEMBL29956486 | 0.77 | MAP4K4 (0.40) | MAP4K4MKNK1MKNK2PARP10PDE4D | |
| SCHEMBL29951686 | 0.77 | MKNK1 (0.44) | MAP4K4MKNK1MKNK2PARP10POLB | |
| SCHEMBL29952137 | 0.75 | AOC3 (0.40) | MAP4K4POLB | |
| SCHEMBL29955972 | 0.73 | PDE4A (0.46) | MAP4K4MKNK1MKNK2PARP10POLB | |
| SCHEMBL29956551 | 0.72 | POLB (0.37) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29951976 | 0.70 | IKBKB (0.38) | MAP4K4MKNK1MKNK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |