Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331377 | 0.87 | NOTUM (0.55) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29954881 | 0.83 | NOTUM (0.52) | NOTUMALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL7444262 | 0.81 | NOTUM (0.60) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3436333 | 0.81 | NOTUM (0.60) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2555349 | 0.78 | NOTUM (0.65) | NOTUM | |
| SCHEMBL29957383 | 0.78 | NOTUM (0.60) | NOTUM | |
| SCHEMBL18503843 | 0.77 | NOTUM (0.49) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15330773 | 0.76 | NOTUM (0.57) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2558871 | 0.76 | NPC1 (0.61) | NOTUMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29950827 | 0.76 | NOTUM (0.57) | NOTUMALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |