Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22807129 | 0.87 | DRD2 (0.47) | NOTUMDRD2APAF1NSD2POLB | |
| SCHEMBL2557896 | 0.85 | NOTUM (0.52) | NOTUMAPAF1NSD2POLBMAPT | |
| SCHEMBL29956491 | 0.83 | NOTUM (0.55) | NOTUMDRD2MAPTKMT2AKDM4E | |
| SCHEMBL3436316 | 0.78 | TSHR (0.58) | NOTUMMAPTKDM4ECYP2C19ALDH1A1 | |
| SCHEMBL5800932 | 0.78 | NOTUM (0.81) | NOTUMAPAF1NSD2POLBMAPT | |
| SCHEMBL2555349 | 0.77 | NOTUM (0.65) | NOTUM | |
| SCHEMBL5798505 | 0.77 | CASP1 (0.58) | NOTUMAPAF1NSD2POLBMAPT | |
| SCHEMBL29957383 | 0.77 | NOTUM (0.60) | NOTUM | |
| SCHEMBL4825361 | 0.76 | DRD2 (0.62) | DRD2MAPTCYP2C19EEDALDH1A1 | |
| SCHEMBL5800091 | 0.75 | NOTUM (0.58) | NOTUMAPAF1NSD2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |