Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957446 | 0.92 | SIGMAR1 (0.60) | SIGMAR1SMN1; SMN2ALDH1A1ATMHPGD | |
| SCHEMBL29956260 | 0.83 | SIGMAR1 (0.51) | SIGMAR1ALDH1A1 | |
| SCHEMBL2560850 | 0.82 | POLB (0.49) | SIGMAR1POLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29956117 | 0.82 | SIGMAR1 (0.47) | SIGMAR1SMYD3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2558828 | 0.81 | POLB (0.47) | SIGMAR1POLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL13661594 | 0.80 | SIGMAR1 (0.64) | SIGMAR1POLBSMYD3SMN1; SMN2L3MBTL1 | |
| SCHEMBL29956997 | 0.79 | POLB (0.46) | SIGMAR1POLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2555804 | 0.78 | HTT (0.45) | SIGMAR1POLBHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29950821 | 0.77 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1HPGD | |
| SCHEMBL2559294 | 0.77 | POLB (0.44) | SIGMAR1POLBHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |