Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 4/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481107 | 1.00 | CLK4 (0.39) | CLK4KDM4CCA1CA2GRM4 | |
| SCHEMBL27751609 | 0.80 | MAP4K4 (0.44) | CA1CA2EGLN2 | |
| SCHEMBL29951370 | 0.80 | HDAC8 (0.41) | CA1CA2CDC7CDK2MAP3K14 | |
| SCHEMBL931149 | 0.80 | MAP3K14 (0.39) | CLK4KDM4CCYP2A6KCNH2NPY5R | |
| SCHEMBL2107129 | 0.76 | GRM5 (0.45) | CA1CA2GRM4 | |
| SCHEMBL19962828 | 0.74 | IDH1 (0.39) | CLK4KDM4CGRM4ALDH1A1IDH1 | |
| SCHEMBL22637043 | 0.73 | CLK4 (0.34) | CLK4KCNH2NPY5RALDH1A1EGLN2 | |
| SCHEMBL28543643 | 0.73 | MEN1 (0.53) | CLK4GRM4CDC7CDK2ALDH1A1 | |
| SCHEMBL2528059 | 0.72 | — | — | |
| SCHEMBL7970820 | 0.72 | MAPKAPK2 (0.40) | CLK4KDM4CKCNH2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |