Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955368 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL2217197 | 0.79 | KDM4E (0.60) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL2230037 | 0.78 | MAPT (0.62) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL21352392 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29954788 | 0.74 | MAPT (0.65) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29956904 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29951842 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29954347 | 0.72 | HPGD (0.77) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL15330884 | 0.72 | KMT2A (1.00) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29953918 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |