Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.45 |
| ▸ | BRAF | P15056 | 5/20 | 0.45 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559867 | 0.96 | SRC (0.51) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL2559640 | 0.96 | SRC (0.51) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL15331816 | 0.93 | POLB (0.46) | SRCBRAFKDRPOLBKDM4E | |
| SCHEMBL11725935 | 0.93 | POLB (0.52) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL15331770 | 0.90 | MAPT (0.38) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL2561813 | 0.90 | POLB (0.40) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL2559095 | 0.89 | MEN1 (0.41) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL2551350 | 0.89 | LMNA (0.40) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL2556503 | 0.89 | SRC (0.55) | SRCBRAFKDRPOLBLMNA | |
| SCHEMBL15332097 | 0.89 | SRC (0.55) | SRCBRAFKDRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |