Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076847 | 1.00 | KIF11 (0.46) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL578196 | 0.86 | TTK (0.52) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL29921404 | 0.86 | TTK (0.52) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL29953125 | 0.80 | KIF11 (0.47) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL3534726 | 0.80 | KIF11 (0.47) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL6526757 | 0.80 | JAK2 (0.55) | KIF11TTKCYP2A6KDM4EJAK2 | |
| SCHEMBL181661 | 0.79 | KIF11 (0.46) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL182436 | 0.79 | KIF11 (0.46) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL17927605 | 0.79 | KIF11 (0.46) | KIF11TTKCYP2A6ALDH1A1KDM4E | |
| SCHEMBL1411783 | 0.79 | KIF11 (0.46) | KIF11TTKCYP2A6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |