Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218325 | 1.00 | MAPT (0.58) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29444102 | 0.75 | MAPT (1.00) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL503252 | 0.75 | MAPT (1.00) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17301945 | 0.75 | RRM2 (0.31) | — | |
| SCHEMBL30366834 | 0.74 | TDP1 (0.58) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3706723 | 0.74 | TDP1 (0.58) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20551851 | 0.74 | MAPT (0.42) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2023434 | 0.74 | ERN1 (0.49) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5101956 | 0.74 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28412041 | 0.74 | KDM4E (0.52) | MAPTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |