Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444102 | 1.00 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8002675 | 0.83 | MAPT (0.70) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12543710 | 0.81 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1128615 | 0.81 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8001010 | 0.81 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30939014 | 0.81 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL121118 | 0.81 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7695642 | 0.79 | ALDH1A1 (0.65) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Phenazine SCHEMBL29356959 | 0.78 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Phenazine SCHEMBL9049 | 0.78 | MAPT (1.00) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380753-B | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2024-02-27 | — | — | CN | claimed |
| CN-116621844-A | Organic nitrogen-containing polyquinone material, preparation method thereof and application thereof in organic lithium ion battery | 常州大学 | 2023-08-22 | — | — | CN | claimed |
| CN-114380753-A | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2022-04-22 | — | — | CN | claimed |
| CN-110867603-B | Polypyrrole-quinoxaline-negative-electrode-based all-water-system mixed flow battery and preparation method thereof | 常州大学 | 2022-03-22 | — | — | CN | claimed |
| CN-110867603-A | Polypyrrole-quinoxaline-negative-electrode-based all-water-system mixed flow battery and preparation method thereof | 常州大学 | 2020-03-06 | — | — | CN | claimed |
| CN-103450885-A | Organic luminescent material based on quinoxaline diamine skeleton and preparation method thereof | UNIV NANYANG NORMAL | 2013-12-18 | — | — | CN | claimed |
| EP-4714954-A1 | FUSED POLYCYCLIC COMPOUNDS AS ELECTRODE ACTIVE MATERIALS FOR AQUEOUS AND NON-AQUEOUS SECONDARY BATTERIES | Kemijski Institut (SI) | 2026-03-25 | — | — | EP | disclosed |
| US-12503448-B2 | Antibacterial and antiparasitic quinoxaline-2,3-diamine derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2025-12-23 | — | — | US | disclosed |
| US-12115158-B2 | Survivin-targeting anti-tumor agents and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-10-15 | — | — | US | disclosed |
| CN-114380753-B | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2024-02-27 | — | — | CN | disclosed |
| CN-114380753-B | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2024-02-27 | — | — | CN | disclosed |
| CN-114380753-B | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2024-02-27 | — | — | CN | disclosed |
| CN-116621844-A | Organic nitrogen-containing polyquinone material, preparation method thereof and application thereof in organic lithium ion battery | 常州大学 | 2023-08-22 | — | — | CN | disclosed |
| US-4022777-A | Imidazoquinoxaline fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-05-10 | — | — | US | disclosed |
| US-4008225-A | Process for the manufacture of bis-azomethine metal complex colorants | CIBA-GEIGY CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-4000135-A | IRON TETRAAZANNULENES AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3987171-A | QUINOXALINE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3963708-A | Bis-azomethine metal complex colorants from hydroxycoumarin derivatives or hydroxychromone derivatives | CIBA-GEIGY CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
| US-3939194-A | Bis-2-azomethine pigments, process for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |
| US-3935312-A | Combating fungi with imidazo-[4,5-b]quinoxalines | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503448-B2 | Antibacterial and antiparasitic quinoxaline-2,3-diamine derivatives | FPR3, RPS12, FPR2 | MAPT 4846/4885KDM4E 3104/4885ALDH1A1 3617/4885 |
| US-12115158-B2 | Survivin-targeting anti-tumor agents and uses thereof | XIAP, BIRC5, TP53 | MAPT 3150/4885KDM4E 4302/4885ALDH1A1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.