Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | DDO | Q99489 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361818 | 1.00 | DAO (0.53) | DAODDOCYP2A6CYP1A2CYP2C19 | |
| SCHEMBL10719586 | 0.78 | CYP2A6 (0.52) | CYP2A6CYP1A2CYP2C19TNKS2KIF11 | |
| SCHEMBL29954679 | 0.78 | DAO (0.53) | DAODDOCYP2A6KIF11FLT3 | |
| SCHEMBL30097055 | 0.78 | CYP2A6 (0.52) | CYP2A6KIF11FLT3AHRMAPT | |
| SCHEMBL7873195 | 0.78 | DAO (0.53) | DAOCYP2A6CYP1A2KIF11FLT3 | |
| SCHEMBL23706033 | 0.78 | CYP2A6 (0.52) | CYP2A6KIF11FLT3AHRMAPT | |
| SCHEMBL30175963 | 0.78 | CYP2A6 (0.52) | DAODDOCYP2A6KIF11TRIM24 | |
| SCHEMBL11708385 | 0.78 | CYP2A6 (0.43) | CYP2A6CYP1A2CYP2C19TNKS2KIF11 | |
| SCHEMBL20839970 | 0.78 | DAO (0.53) | DAODDOCYP2A6KIF11FLT3 | |
| SCHEMBL29956059 | 0.78 | DAO (0.53) | DAOCYP2A6CYP1A2KIF11FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |