Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706033 | 1.00 | CYP2A6 (0.52) | CYP2A6PIM1PIM3PIM2FLT3 | |
| SCHEMBL29954679 | 0.78 | DAO (0.53) | CYP2A6FLT3HRH4AHRKIF11 | |
| SCHEMBL29956806 | 0.78 | DAO (0.53) | CYP2A6FLT3AHRKIF11MEN1 | |
| SCHEMBL29956059 | 0.78 | DAO (0.53) | CYP2A6FLT3HRH4AHRKIF11 | |
| SCHEMBL5361818 | 0.78 | DAO (0.53) | CYP2A6FLT3AHRKIF11MEN1 | |
| SCHEMBL7873195 | 0.78 | DAO (0.53) | CYP2A6FLT3HRH4AHRKIF11 | |
| SCHEMBL10719586 | 0.78 | CYP2A6 (0.52) | CYP2A6PIM1PIM3PIM2AHR | |
| SCHEMBL30175963 | 0.78 | CYP2A6 (0.52) | CYP2A6HRH4AHRKIF11MEN1 | |
| SCHEMBL20839970 | 0.78 | DAO (0.53) | CYP2A6FLT3HRH4AHRKIF11 | |
| SCHEMBL25651019 | 0.78 | CYP2A6 (0.52) | CYP2A6HRH4AHRKIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |