Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557736 | 0.86 | ORAI1 (0.46) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2556737 | 0.83 | TDP1 (0.49) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2556053 | 0.81 | ALDH1A1 (0.53) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL5882741 | 0.78 | ALDH1A1 (0.46) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11781754 | 0.78 | ALDH1A1 (0.57) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2562001 | 0.78 | ALDH1A1 (0.48) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL5883224 | 0.78 | ORAI1 (0.56) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL5881855 | 0.78 | ORAI1 (0.49) | ORAI1ERN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL8189636 | 0.77 | ORAI1 (0.51) | ORAI1ERN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL7812376 | 0.77 | ORAI1 (0.43) | ORAI1ERN1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |