Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954247 | 0.89 | ERN1 (0.49) | TRIM24TYRTRIM33ALDH1A1ERN1 | |
| SCHEMBL27060303 | 0.85 | KCNQ3 (0.43) | ALDH1A1NPC1RAB9AGAALMNA | |
| SCHEMBL29950861 | 0.84 | HPGD (0.46) | HPGDLMNAPOLBKMT2ANPSR1 | |
| SCHEMBL6162530 | 0.83 | CA12 (0.38) | KDM4EHPGDGAAMAPTBRAF | |
| SCHEMBL17084899 | 0.83 | TRIM24 (0.51) | TRIM24TYRTRIM33ALDH1A1ERN1 | |
| SCHEMBL30981444 | 0.83 | TRIM24 (0.51) | TRIM24TYRTRIM33ALDH1A1ERN1 | |
| SCHEMBL29951652 | 0.82 | KCNQ4 (0.43) | RAB9AMAPTLMNAPOLBBRAF | |
| SCHEMBL29950591 | 0.82 | HSP90AA1 (0.43) | ALDH1A1ERN1KDM4EGAAMAPT | |
| SCHEMBL29407156 | 0.82 | RAB9A (0.45) | ERN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27969573 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4EHPGDF10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |