Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956571 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL25458561 | 0.76 | TSHR (0.38) | ALDH1A1TSHRSLC2A1 | |
| SCHEMBL21942117 | 0.76 | TSHR (0.41) | ALDH1A1TSHR | |
| SCHEMBL29950931 | 0.75 | — | — | |
| SCHEMBL29950549 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL29950725 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27497222 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL10766714 | 0.71 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL29950565 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL12725369 | 0.71 | SLC2A1 (0.36) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |