SCHEMBL29956925

SCHEMBL29956925

Cc1cccc(C=O)c1C=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
TSHR P16473 1/20 0.62
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
LMNA P02545 1/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
TRIM24 O15164 2/20 0.46
TRIM33 Q9UPN9 2/20 0.46
ERN1 O75460 3/20 0.41
TLR2 O60603 1/20 0.39
TLR1 Q15399 1/20 0.39
TLR6 Q9Y2C9 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CYP2A6 P11509 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548632 1.00 ALDH1A1 (0.62) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL66979 0.85 ALDH1A1 (0.52) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL16790878 0.85 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL11852153 0.85 ALDH1A1 (0.56) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL29080267 0.84 ALDH1A1 (0.46) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL14529781 0.83 ALDH1A1 (0.54) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL28641344 0.82 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL547829 0.82 KMT2A (0.61) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL31231131 0.78 ALDH1A1 (0.53) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL29444 0.78 TSHR (0.65) ALDH1A1TSHRMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116940559-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-10-24 CN disclosed
CN-116829618-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-09-29 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed