Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 14/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005658 | 0.87 | CCNE1 (0.49) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL2999175 | 0.86 | CCNE1 (0.37) | CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL3000249 | 0.85 | PDE4A (0.38) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL2988381 | 0.82 | CDK2 (0.36) | CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL2995160 | 0.82 | ADORA2A (0.35) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL2995698 | 0.82 | HSP90AB1 (0.42) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL2912438 | 0.80 | HSP90AB1 (0.39) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL2996736 | 0.80 | HDAC1 (0.45) | — | |
| SCHEMBL2996929 | 0.79 | CYP1A2 (0.40) | CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL3005457 | 0.78 | ADORA2A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |