Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005658 | 0.90 | CCNE1 (0.49) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL2995693 | 0.86 | HSP90AB1 (0.42) | CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL3000249 | 0.85 | PDE4A (0.38) | CCNE1CDK2CDK1CCNB1 | |
| SCHEMBL2988381 | 0.83 | CDK2 (0.36) | CCNE1CDK2CDK1CCNB1ADORA1 | |
| SCHEMBL2996736 | 0.82 | HDAC1 (0.45) | HDAC1HDAC6 | |
| SCHEMBL2999182 | 0.82 | CCNE1 (0.36) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL2996929 | 0.81 | CYP1A2 (0.40) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL3005457 | 0.80 | ADORA2A (0.48) | ADORA2AADORA1 | |
| SCHEMBL2995160 | 0.79 | ADORA2A (0.35) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL2911369 | 0.79 | PNP (0.35) | CCNE1CDK2CDK1CCNB1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |