Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.46 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.43 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992735 | 1.00 | CYP3A4 (0.48) | CYP3A4TSHRTDP1ING2DUSP5 | |
| SCHEMBL18538307 | 0.88 | SLC6A2 (0.40) | CYP3A4TSHRTDP1ING2DUSP5 | |
| SCHEMBL18538303 | 0.74 | ING2 (0.68) | ING2DUSP5DUSP6PTPRBCA1 | |
| SCHEMBL29634901 | 0.71 | ING2 (0.46) | CYP3A4ING2DUSP5DUSP6PTPRB | |
| SCHEMBL13287042 | 0.71 | SELL (0.48) | CYP3A4ING2DUSP5DUSP6PTPRB | |
| SCHEMBL979162 | 0.69 | CYP19A1 (0.32) | — | |
| SCHEMBL14848401 | 0.65 | ING2 (0.46) | TDP1ING2DUSP5DUSP6PTPRB | |
| SCHEMBL13620669 | 0.65 | GABRA1 (0.50) | TDP1ING2DUSP5DUSP6GABRA1 | |
| SCHEMBL21260624 | 0.65 | GABRA1 (0.46) | ING2DUSP5DUSP6GABRA1GABRB1 | |
| SCHEMBL2471228 | 0.65 | GABRA1 (0.50) | TDP1ING2DUSP5DUSP6GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11027257-B2 | Polycalixarene materials, methods of making same, and uses thereof | NEW YORK UNIVERSITY IN ABU DHABI CORPORATION (AE) | 2021-06-08 | — | — | US | claimed |
| US-20190015814-A1 | POLYCALIXARENE MATERIALS, METHODS OF MAKING SAME, AND USES THEREOF | NEW YORK UNIVERSITY IN ABU DHABI CORPORATION (AE) | 2019-01-17 | — | — | US | claimed |
| US-11027257-B2 | Polycalixarene materials, methods of making same, and uses thereof | NEW YORK UNIVERSITY IN ABU DHABI CORPORATION (AE) | 2021-06-08 | — | — | US | disclosed |
| US-20190015814-A1 | POLYCALIXARENE MATERIALS, METHODS OF MAKING SAME, AND USES THEREOF | NEW YORK UNIVERSITY IN ABU DHABI CORPORATION (AE) | 2019-01-17 | — | — | US | disclosed |
| US-8252954-B2 | Processes for the preparation of calixarene derivatives | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2012-08-28 | — | — | US | disclosed |
| US-20100185022-A1 | PROCESSES FOR THE PREPARATION OF CALIXARENE DERIVATIVES | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100185022-A1 | PROCESSES FOR THE PREPARATION OF CALIXARENE DERIVATIVES | CALD1, CANX, CALU | CYP3A4 1663/4885TSHR 4061/4885TDP1 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.