Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 6/20 | 0.40 |
| ▸ | PAICS | P22234 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222191 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL23147699 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL2893597 | 0.86 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL14721607 | 0.84 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL30484274 | 0.82 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL26458925 | 0.82 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL28430679 | 0.81 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL28522216 | 0.78 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KDM4EHRH3POLB | |
| SCHEMBL2004014 | 0.77 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL24400515 | 0.77 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4EHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |