Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601817 | 0.83 | MEN1 (0.64) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8505144 | 0.81 | PTGER4 (0.49) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29878719 | 0.81 | PTGER4 (0.49) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8503543 | 0.80 | MEN1 (0.43) | MAPTHPGDMEN1KMT2AKDM4E | |
| SCHEMBL29951644 | 0.80 | PTGER4 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1144602 | 0.79 | KDM4E (0.53) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL25225487 | 0.78 | KDM4E (0.50) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29360556 | 0.78 | PTGER4 (0.52) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL24522324 | 0.78 | PTGER4 (0.52) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7603198 | 0.77 | ALDH1A1 (0.65) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |