Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | AOC1 | P19801 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896645 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL29958176 | 0.82 | GAA (0.46) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL361105 | 0.82 | GAA (0.46) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| Hydrochloric Acid SCHEMBL29956207 | 0.80 | GAA (0.45) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| Hydrochloric Acid SCHEMBL1301715 | 0.80 | GAA (0.45) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL29952734 | 0.74 | KDM4E (0.38) | KDM4ETDP1KDM4CEP300KAT2B | |
| SCHEMBL22489854 | 0.74 | KDM4E (0.38) | KDM4ETDP1KDM4CEP300KAT2B | |
| SCHEMBL708913 | 0.74 | SIRT3 (0.41) | MAPTTDP1GAACYP2D6CYP1A2 | |
| SCHEMBL115776 | 0.73 | GAA (0.46) | MAPTKDM4ETDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14797240 | 0.73 | SIRT3 (0.39) | TDP1GAACYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |