Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PRKCI | P41743 | 4/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 4/20 | 0.47 |
| ▸ | CHUK | O15111 | 4/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634449 | 1.00 | KMT2A (0.56) | KMT2APRKCIAXLCCR1CCR5 | |
| SCHEMBL859116 | 0.79 | NUDT1 (0.58) | KMT2APRKCIIKBKBCHUKAURKB | |
| SCHEMBL2878947 | 0.76 | PARP1 (0.52) | KMT2APRKCIAXLIKBKBCHUK | |
| SCHEMBL2878942 | 0.76 | PARP1 (0.52) | KMT2APRKCIAXLIKBKBCHUK | |
| SCHEMBL857030 | 0.75 | IKBKB (0.47) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL15068357 | 0.74 | NUDT1 (0.40) | KMT2APRKCIAXLCCR1CCR5 | |
| SCHEMBL1135006 | 0.74 | PRKCI (0.59) | KMT2APRKCIAXLIKBKBCHUK | |
| SCHEMBL29817501 | 0.74 | PRKCI (0.59) | KMT2APRKCIAXLIKBKBCHUK | |
| SCHEMBL29605623 | 0.74 | NUDT1 (0.61) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL21062776 | 0.74 | PRKCI (0.59) | PRKCIAXLIKBKBCHUKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684287-A | 4- (3- (Piperidin-4-yl) -1H-pyrazol-5-yl) -1H-pyrrole [2,3-b ] pyridine derivative, and preparation method and application thereof | 烟台新药创制山东省实验室 | 2025-03-25 | — | — | CN | claimed |
| CN-120058674-A | 4 (1H-pyrazol-3-yl) piperidinyl derivative, preparation method thereof and application thereof in preparation of MNK inhibitor | 烟台新药创制山东省实验室 | 2025-05-30 | — | — | CN | disclosed |
| CN-119684287-A | 4- (3- (Piperidin-4-yl) -1H-pyrazol-5-yl) -1H-pyrrole [2,3-b ] pyridine derivative, and preparation method and application thereof | 烟台新药创制山东省实验室 | 2025-03-25 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |