Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000884 | 0.88 | SERPINE1 (0.62) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL30821431 | 0.88 | SERPINE1 (0.62) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL3006064 | 0.86 | SERPINE1 (0.48) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL2991316 | 0.84 | SERPINE1 (0.45) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL3000109 | 0.83 | SERPINE1 (0.51) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL3000837 | 0.80 | ESR1 (0.56) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL10960406 | 0.77 | NSD2 (0.70) | KMT2AMEN1MAPTTDP1ALOX5 | |
| SCHEMBL9967346 | 0.76 | CA12 (0.58) | KMT2AMEN1MAPTTDP1SERPINE1 | |
| SCHEMBL15103581 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1MAPTTDP1GAA | |
| SCHEMBL18697311 | 0.74 | ALDH1A1 (0.39) | KMT2AMEN1MAPTTDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | claimed |
| EP-2019091-A1 | Novel polyhydroxylated compounds as Fatty Acid Synthase (FASN) inhibitors | Fundació Privada Institut d'Investigació Biomédica de Girona - Dr. Josep Trueta (ES) | 2009-01-28 | — | — | EP | claimed |
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | disclosed |
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | disclosed |
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2010-07-29 | — | — | US | disclosed |
| EP-2019091-A1 | Novel polyhydroxylated compounds as Fatty Acid Synthase (FASN) inhibitors | Fundació Privada Institut d'Investigació Biomédica de Girona - Dr. Josep Trueta (ES) | 2009-01-28 | — | — | EP | disclosed |
| EP-2019091-A1 | Novel polyhydroxylated compounds as Fatty Acid Synthase (FASN) inhibitors | Fundació Privada Institut d'Investigació Biomédica de Girona - Dr. Josep Trueta (ES) | 2009-01-28 | — | — | EP | disclosed |
| WO-2009000864-A1 | NOVEL POLYHYDROXYLATED COMPOUNDS AS FATTY ACID SYNTHASE (FASN) INHIBITORS | FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA (ES) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190856-A1 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors | FASN, SCD, FADS2 | KMT2A 3556/4885MEN1 4821/4885MAPT 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.