Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.57 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490536 | 1.00 | KDM4E (0.57) | KDM4EMETAP2MMP2CHRM1TSHR | |
| Formamide SCHEMBL9732098 | 0.83 | PARP1 (0.62) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL18573144 | 0.83 | KDM4E (0.57) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL9732094 | 0.82 | KDM4E (0.49) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL27398936 | 0.79 | PARP1 (0.43) | KDM4EPARP1NPC1 | |
| SCHEMBL26590078 | 0.79 | PARP1 (0.43) | KDM4EPARP1KMT2A | |
| SCHEMBL29022258 | 0.79 | CCR1 (0.46) | KDM4EPARP1 | |
| SCHEMBL20176009 | 0.76 | KDM4E (0.62) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL29953052 | 0.76 | ERN1 (0.54) | KDM4EMETAP2MMP2CHRM1TSHR | |
| SCHEMBL28592203 | 0.76 | ERN1 (0.54) | KDM4EMETAP2MMP2CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |