Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450325 | 1.00 | MAPT (0.32) | MAPTALDH1A1KDM4ENPC1CYP1A2 | |
| SCHEMBL109642 | 0.79 | — | — | |
| SCHEMBL4142457 | 0.79 | MAPT (0.34) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1752166 | 0.77 | GPR3 (0.32) | MAPTALDH1A1KDM4ENPC1CYP1A2 | |
| SCHEMBL1751841 | 0.77 | GPR3 (0.32) | ALDH1A1KDM4ENPC1CYP1A2CYP3A4 | |
| SCHEMBL29957143 | 0.76 | PRMT5 (0.32) | NPC1 | |
| SCHEMBL4486828 | 0.76 | PRMT5 (0.32) | NPC1 | |
| SCHEMBL29953424 | 0.76 | SSTR4 (0.30) | — | |
| SCHEMBL15024911 | 0.75 | SMN1; SMN2 (0.33) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3450328 | 0.72 | KDM4E (0.31) | ALDH1A1KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |