SCHEMBL2995746

SCHEMBL2995746

CCCCCCCCC(=O)CCC(C)(C)CC(=O)CCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
MAPT P10636 1/20 0.53
CES2 O00748 4/20 0.45
CES1 P23141 4/20 0.45
HAO1 Q9UJM8 1/20 0.44
GPR84 Q9NQS5 7/20 0.43
PPARG P37231 7/20 0.43
PPARD Q03181 7/20 0.43
PPARA Q07869 7/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
PTPN1 P18031 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8896261 0.90 KMT2A (0.50) KMT2AMAPTCES2CES1HAO1
SCHEMBL2994225 0.88 KMT2A (0.56) KMT2AMAPTCES2CES1HAO1
SCHEMBL8897417 0.86 KMT2A (0.55) KMT2AMAPTCES2CES1HAO1
SCHEMBL18670992 0.86 KMT2A (0.55) KMT2AMAPTCES2CES1HAO1
SCHEMBL8895698 0.86 TDP1 (0.52) KMT2AMAPTCES2CES1HAO1
SCHEMBL8096569 0.84 KMT2A (0.52) KMT2AMAPTCES2CES1HAO1
SCHEMBL8898144 0.84 KMT2A (0.52) KMT2AMAPTCES2CES1HAO1
SCHEMBL8897068 0.84 KMT2A (0.52) KMT2AMAPTCES2CES1HAO1
SCHEMBL9177158 0.84 KMT2A (0.52) KMT2AMAPTCES2CES1HAO1
SCHEMBL7267299 0.82 TSHR (0.44) KMT2AMAPTHAO1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
US-4521324-A Fluid for traction drive IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-06-04 US disclosed