Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896261 | 0.84 | KMT2A (0.50) | TSHRFAAHMAPTKMT2AHSD17B10 | |
| SCHEMBL2995746 | 0.82 | KMT2A (0.53) | TSHRFAAHMAPTKMT2AHSD17B10 | |
| SCHEMBL2994225 | 0.82 | KMT2A (0.56) | TSHRFAAHMAPTKMT2AHSD17B10 | |
| SCHEMBL8895698 | 0.80 | TDP1 (0.52) | TSHRMAPTKMT2AHSD17B10FABP4 | |
| SCHEMBL8897068 | 0.78 | KMT2A (0.52) | TSHRFAAHMAPTKMT2AHSD17B10 | |
| SCHEMBL8096569 | 0.78 | KMT2A (0.52) | TSHRFAAHMAPTKMT2AHSD17B10 | |
| SCHEMBL9177158 | 0.78 | KMT2A (0.52) | TSHRFAAHMAPTKMT2AHSD17B10 | |
| SCHEMBL23855776 | 0.76 | TSHR (0.70) | TSHRFAAHMAPTKMT2ATRPV1 | |
| SCHEMBL3200849 | 0.76 | TSHR (0.70) | TSHRFAAHMAPTKMT2ATRPV1 | |
| SCHEMBL3308698 | 0.76 | TSHR (0.70) | TSHRFAAHMAPTKMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328978-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1989-08-23 | — | — | EP | disclosed |