Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566594 | 0.87 | ERN1 (0.53) | CYSLTR2CYSLTR1KDM4EALDH1A1GAA | |
| SCHEMBL27985742 | 0.85 | CCR1 (0.41) | CYSLTR2CYSLTR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30647279 | 0.85 | LCK (0.47) | KDM4ECCR1PFKFB3L3MBTL1ERN1 | |
| SCHEMBL16620892 | 0.81 | HTT (0.56) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL24977227 | 0.77 | KDM4E (0.40) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL16621169 | 0.77 | ALDH1A1 (0.51) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL31428804 | 0.77 | KDM4E (0.40) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29957739 | 0.77 | PFKFB3 (0.54) | CYSLTR2CYSLTR1KDM4ENPC1RAB9A | |
| SCHEMBL1309231 | 0.77 | TDP1 (0.50) | TDP1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL27558490 | 0.77 | PFKFB3 (0.54) | CYSLTR2CYSLTR1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |