Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330690 | 0.93 | TSHR (0.54) | KMT2AHPGDTSHRHSD17B10RAB9A | |
| SCHEMBL2557772 | 0.88 | HPGD (0.62) | KMT2AHPGDTSHRHSD17B10ATM | |
| SCHEMBL2561844 | 0.87 | TSHR (0.53) | KMT2AHPGDTSHRHSD17B10POLB | |
| SCHEMBL2559563 | 0.85 | HPGD (0.73) | KMT2AHPGDTSHRHSD17B10POLB | |
| SCHEMBL28416273 | 0.84 | HPGD (0.71) | KMT2AHPGDTSHRHSD17B10ATM | |
| SCHEMBL2560342 | 0.84 | KMT2A (0.52) | KMT2AHPGDTSHRHSD17B10POLB | |
| SCHEMBL2562343 | 0.82 | HPGD (0.48) | KMT2AHPGDTSHRHSD17B10POLB | |
| SCHEMBL2560250 | 0.82 | HPGD (0.48) | KMT2AHPGDTSHRHSD17B10ATM | |
| SCHEMBL15332743 | 0.82 | PKM (0.49) | KMT2AHPGDTSHRPOLBRAB9A | |
| SCHEMBL2559435 | 0.81 | MEN1 (0.49) | KMT2AHPGDTSHRHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |