Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.58 |
| ▸ | IKBKB | O14920 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641390 | 1.00 | MAPT (0.63) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2285909 | 0.89 | GAA (0.69) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1271606 | 0.87 | GAA (0.67) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6289248 | 0.87 | GAA (0.67) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1270588 | 0.87 | GAA (0.67) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6289955 | 0.87 | GAA (0.67) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6293151 | 0.85 | GAA (0.64) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6289853 | 0.85 | GAA (0.64) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6290392 | 0.85 | GAA (0.64) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1269990 | 0.85 | GAA (0.64) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124463-B | Substituted quinoline compound and preparation method and application thereof | 浙江工业大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-115124463-A | Substituted quinoline compound and preparation method and application thereof | 浙江工业大学 | 2022-09-30 | — | — | CN | disclosed |