Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15751065 | 1.00 | TSHR (0.68) | TSHRSMN1; SMN2APEX1MEN1KMT2A | |
| SCHEMBL3409012 | 0.90 | TSHR (0.65) | TSHRSMN1; SMN2APEX1MEN1KMT2A | |
| SCHEMBL29955875 | 0.90 | TSHR (0.65) | TSHRSMN1; SMN2APEX1MEN1KMT2A | |
| SCHEMBL16195679 | 0.86 | ALDH1A1 (0.64) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29957788 | 0.86 | ALDH1A1 (0.64) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29957713 | 0.85 | MEN1 (0.64) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL12757098 | 0.84 | SMN1; SMN2 (0.75) | TSHRSMN1; SMN2APEX1MEN1KMT2A | |
| SCHEMBL25160259 | 0.84 | SMN1; SMN2 (0.66) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30349891 | 0.84 | SMN1; SMN2 (0.66) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL12218547 | 0.84 | TSHR (0.69) | TSHRSMN1; SMN2APEX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |