Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 6/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700932 | 1.00 | NOS1 (0.38) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL1285358 | 0.77 | KDR (0.45) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL11132639 | 0.77 | NOS1 (0.52) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL1285858 | 0.76 | SYK (0.35) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL1285628 | 0.74 | NOS1 (0.41) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL520456 | 0.74 | NOS1 (0.41) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL15759798 | 0.74 | NOS1 (0.44) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL1285298 | 0.74 | NOS1 (0.41) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL1285709 | 0.73 | CREBBP (0.41) | NOS1NOS3NOS2SYKGRM5 | |
| SCHEMBL1286048 | 0.73 | TTR (0.41) | NOS1NOS3NOS2SYKGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |