SCHEMBL29957746

SCHEMBL29957746

N[C@@H](C(=O)O)c1ccc(C=O)cn1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.34
KCNJ1 P48048 1/20 0.34
P4HTM Q9NXG6 1/20 0.33
GRIK1 P39086 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP3A4 P08684 1/20 0.33
SLC7A5 Q01650 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952100 1.00 ALDH1A1 (0.37) ALDH1A1L3MBTL1KDM4EKCNJ1P4HTM
SCHEMBL15329802 0.77 ALDH1A1 (0.35) ALDH1A1L3MBTL1KDM4EKCNJ1
SCHEMBL15332266 0.77 ALDH1A1 (0.35) ALDH1A1L3MBTL1KDM4EKCNJ1
SCHEMBL2558733 0.77 TYR (0.41) ALDH1A1L3MBTL1KDM4EKCNJ1
SCHEMBL15330759 0.77 TYR (0.41) ALDH1A1L3MBTL1KDM4EKCNJ1
SCHEMBL28470383 0.77 MEN1 (0.43) ALDH1A1KDM4EHSD17B10CYP3A4SLC7A5
SCHEMBL15332988 0.75 ALDH1A1 (0.36) ALDH1A1L3MBTL1KDM4EKCNJ1HSD17B10
SCHEMBL14584180 0.75 MAPT (0.42)
SCHEMBL31574629 0.75 ALDH1A1 (0.48) ALDH1A1KDM4E
SCHEMBL15331595 0.75 ALDH1A1 (0.36) ALDH1A1L3MBTL1KDM4EKCNJ1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed