Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257945 | 1.00 | LMNA (0.56) | LMNATDP1CYP19A1NPC1GAA | |
| SCHEMBL13857858 | 0.81 | CA1 (0.53) | TDP1LTA4HFFAR4 | |
| SCHEMBL2555152 | 0.81 | CYP3A4 (0.38) | — | |
| SCHEMBL12330285 | 0.80 | LMNA (0.61) | LMNATDP1CYP19A1NPC1GAA | |
| SCHEMBL177751 | 0.80 | SLC6A2 (0.42) | FFAR4 | |
| SCHEMBL2562128 | 0.79 | P2RY14 (0.35) | — | |
| SCHEMBL257909 | 0.78 | F9 (0.46) | LMNACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL258021 | 0.77 | SOS1 (0.46) | FFAR4 | |
| SCHEMBL12260750 | 0.77 | LMNA (0.61) | LMNATDP1CYP19A1NPC1GAA | |
| SCHEMBL257633 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |