SCHEMBL2995779

SCHEMBL2995779

CC(CC(C)C)=NNC(=O)c1ccncc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.56
TDP1 Q9NUW8 1/20 0.56
GAA P10253 6/20 0.55
ALDH1A1 P00352 6/20 0.53
MAPT P10636 5/20 0.53
IDE P14735 1/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
GFER P55789 1/20 0.51
LMNA P02545 1/20 0.50
RAB9A P51151 1/20 0.50
CYP3A4 P08684 1/20 0.50
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2995777 1.00 KDM4E (0.56) KDM4ETDP1GAAALDH1A1MAPT
SCHEMBL6055303 0.86 GAA (0.58) KDM4ETDP1GAAALDH1A1MAPT
SCHEMBL3003239 0.85 KDM4E (0.54) KDM4ETDP1GAAALDH1A1MAPT
SCHEMBL3003242 0.85 KDM4E (0.54) KDM4ETDP1GAAALDH1A1MAPT
SCHEMBL1562806 0.84 SMN1; SMN2 (0.65) KDM4ETDP1ALDH1A1MAPTKMT2A
SCHEMBL1562807 0.84 SMN1; SMN2 (0.65) KDM4ETDP1ALDH1A1MAPTKMT2A
SCHEMBL6637074 0.84 SMN1; SMN2 (0.65) KDM4ETDP1ALDH1A1MAPTKMT2A
SCHEMBL31141986 0.83 KDM4E (0.67) KDM4ETDP1GAAALDH1A1MAPT
SCHEMBL29158233 0.83 KDM4E (0.67) KDM4ETDP1GAAALDH1A1MAPT
SCHEMBL6635773 0.83 KDM4E (0.60) KDM4ETDP1GAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP claimed
US-20240317978-A1 RUBBER COMPOSITION AND TIRE OTSUKA CHEMICAL CO., LTD. (JP) 2024-09-26 US disclosed
CN-117561303-A Rubber composition and tire 大塚化学株式会社 2024-02-13 CN disclosed
WO-2023277057-A1 RUBBER COMPOSITION AND TIRE 大塚化学株式会社 2023-01-05 WO disclosed
US-20100184811-A1 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) 2010-07-22 US disclosed
EP-2068873-A2 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS Pharma 2100 (DK) 2009-06-17 EP disclosed
WO-2008031440-A2 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS PHARMA 2100 (DK) 2008-03-20 WO disclosed
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP disclosed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 EP disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 US disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 EP disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184811-A1 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS ODC1, OTC, ACACB KDM4E 3169/4885TDP1 3641/4885GAA 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.