Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991665 | 1.00 | KDM4E (0.60) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2991662 | 1.00 | KDM4E (0.60) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2993090 | 0.87 | KDM4E (0.58) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2993091 | 0.87 | KDM4E (0.58) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL3003219 | 0.87 | GAA (0.63) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL3003222 | 0.87 | GAA (0.63) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2988292 | 0.85 | GAA (0.63) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2998242 | 0.84 | OGG1 (0.61) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2998244 | 0.84 | OGG1 (0.61) | KDM4ETDP1GAAMAPTALDH1A1 | |
| SCHEMBL2984372 | 0.84 | GAA (0.60) | KDM4ETDP1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |