Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816427 | 1.00 | CYP1A2 (0.62) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL29951198 | 1.00 | CYP1A2 (0.62) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL14030650 | 0.86 | CYP1A2 (0.52) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL5364992 | 0.85 | LTA4H (0.58) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL28222826 | 0.84 | CYP1A2 (0.50) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL10376563 | 0.83 | CYP1A2 (0.65) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL28681011 | 0.81 | ACE2 (0.56) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL28310395 | 0.81 | ACE2 (0.56) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL28673361 | 0.81 | ACE2 (0.56) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL1985416 | 0.80 | FOLH1 (0.38) | CYP1A2GABRR1BLMLMNAGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |