Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 14/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018246 | 0.89 | ERN1 (0.74) | ERN1 | |
| SCHEMBL29953817 | 0.89 | ERN1 (0.74) | ERN1 | |
| SCHEMBL29951315 | 0.85 | ERN1 (0.66) | ERN1CDK8 | |
| SCHEMBL29952332 | 0.83 | PLK1 (0.47) | ERN1HDAC8HDAC6CDK8 | |
| SCHEMBL15331501 | 0.82 | ERN1 (0.77) | ERN1 | |
| SCHEMBL29955051 | 0.81 | ERN1 (0.72) | ERN1MAP4K4 | |
| SCHEMBL13702375 | 0.81 | HDAC8 (0.68) | CRBNHDAC8HDAC6CDK8PDK2 | |
| SCHEMBL2552977 | 0.81 | ERN1 (0.78) | ERN1 | |
| SCHEMBL12651049 | 0.81 | CRBN (0.54) | ERN1CRBNHDAC8HDAC6CDK8 | |
| SCHEMBL29954336 | 0.79 | ERN1 (0.48) | ERN1HDAC8HDAC6CDK8PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |