Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948587 | 1.00 | NR1H2 (0.44) | NR1H2SRD5A2ALOX5NR1H3MAOB | |
| SCHEMBL1180319 | 0.92 | SRD5A2 (0.52) | NR1H2SRD5A2ALOX5NR1H3MAOB | |
| SCHEMBL12996827 | 0.85 | NR1H2 (0.43) | NR1H2NR1H3MEN1KMT2A | |
| SCHEMBL17355643 | 0.84 | SRD5A2 (0.51) | NR1H2SRD5A2ALOX5NR1H3MAOB | |
| SCHEMBL12829958 | 0.84 | NR1H2 (0.47) | NR1H2NR1H3MAOB | |
| SCHEMBL25678073 | 0.82 | NR1H2 (0.44) | NR1H2SRD5A2ALOX5NR1H3MAOB | |
| SCHEMBL29953334 | 0.82 | NR1H2 (0.45) | NR1H2NR1H3 | |
| SCHEMBL513258 | 0.82 | NR1H2 (0.45) | NR1H2NR1H3 | |
| SCHEMBL23970708 | 0.80 | GRM5 (0.37) | NR1H2NR1H3YAP1MEN1KMT2A | |
| SCHEMBL29642333 | 0.80 | GRM5 (0.37) | NR1H2NR1H3YAP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |