Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621085 | 0.85 | PDE5A (0.47) | PDE4APDE4BPDE4CPDE4DMKNK1 | |
| SCHEMBL4585947 | 0.80 | SCN9A (0.56) | ADRB1ADRB3ADRB2 | |
| SCHEMBL11674721 | 0.79 | ALDH1A1 (0.55) | PDE4APDE4BPDE4CPDE4DADRB1 | |
| SCHEMBL4584962 | 0.79 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DADRB1 | |
| SCHEMBL21939128 | 0.78 | GRIK1 (0.55) | PDE4APDE4BPDE4CPDE4DADRB1 | |
| SCHEMBL2889886 | 0.78 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10790302 | 0.75 | EPHX2 (0.51) | ADRB1ADRB3FABP4FABP5 | |
| SCHEMBL29483330 | 0.75 | EPHX2 (0.51) | ADRB1ADRB3FABP4FABP5 | |
| SCHEMBL10790141 | 0.75 | EPHX2 (0.51) | ADRB1ADRB3FABP4FABP5 | |
| SCHEMBL300806 | 0.75 | EPHX2 (0.51) | ADRB1ADRB3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |