Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957196 | 0.84 | KMT2A (0.56) | KMT2ACYP2A6JAK2CCR1CCR5 | |
| SCHEMBL29952688 | 0.79 | KMT2A (0.51) | KMT2ACYP2A6JAK2CCR1CCR5 | |
| SCHEMBL857522 | 0.79 | LRRK2 (0.53) | KMT2ACYP2A6CCR1CCR5CCR8 | |
| SCHEMBL672053 | 0.79 | CYP2A6 (0.51) | KMT2ACYP2A6CCR1CCR5CCR8 | |
| SCHEMBL4530465 | 0.79 | LRRK2 (0.53) | KMT2ACYP2A6CCR1CCR5CCR8 | |
| SCHEMBL29952362 | 0.79 | KMT2A (0.51) | KMT2ACYP2A6JAK2CCR1CCR5 | |
| SCHEMBL17843962 | 0.79 | KMT2A (0.51) | KMT2ACYP2A6JAK2CCR1CCR5 | |
| SCHEMBL29951288 | 0.79 | KMT2A (0.47) | KMT2ACYP2A6KDM4EMEN1NPC1 | |
| SCHEMBL20757818 | 0.77 | KMT2A (0.49) | KMT2ACYP2A6JAK2CCR1CCR5 | |
| SCHEMBL29951249 | 0.76 | CCNT1 (0.51) | KMT2AKDM4ECDK9HASPINCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |