Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 5/20 | 0.51 |
| ▸ | CDK9 | P50750 | 5/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SIK1 | P57059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27869093 | 0.82 | KMT2A (0.43) | CCNT1CDK9CDK5CDK5R1CCNA2 | |
| SCHEMBL29957196 | 0.80 | KMT2A (0.56) | CCNT1CDK9CDK5CDK5R1CCNA2 | |
| SCHEMBL17843962 | 0.79 | KMT2A (0.51) | CCNT1CDK9CDK5KMT2AHTR2A | |
| SCHEMBL1951472 | 0.78 | MAP2K1 (0.50) | KMT2AALDH1A1KDM4E | |
| SCHEMBL29954463 | 0.78 | MAP2K1 (0.50) | KMT2AALDH1A1KDM4E | |
| SCHEMBL26612367 | 0.77 | MAP3K7 (0.46) | KMT2AALDH1A1MAPT | |
| SCHEMBL29956991 | 0.77 | KMT2A (0.36) | CCNT1CDK9CDK5CDK5R1CCNA2 | |
| SCHEMBL19478523 | 0.77 | CDK2 (0.56) | CCNT1CDK9CDK5CDK5R1CCNA2 | |
| SCHEMBL20757818 | 0.76 | KMT2A (0.49) | CCNT1CDK9CDK5CDK5R1CCNA2 | |
| SCHEMBL25249416 | 0.76 | CCNT1 (0.55) | CCNT1CDK9CDK5CDK5R1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |