Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677351 | 0.88 | SIRT1 (0.52) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL1030124 | 0.85 | PI4KB (0.50) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL2175797 | 0.85 | SMN1; SMN2 (0.50) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL27853416 | 0.84 | SIRT1 (0.46) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL356279 | 0.83 | SMN1; SMN2 (0.64) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL13033265 | 0.83 | SIRT1 (0.49) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL9071272 | 0.83 | SIRT1 (0.49) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL6679893 | 0.83 | SIRT1 (0.49) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL16123390 | 0.83 | SIRT1 (0.52) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL2668976 | 0.83 | SIRT1 (0.47) | SIRT1PI4KBSMN1; SMN2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |